Riken and Spinout TagCyx Develop Synthetic Base Pair Exhibiting High PCR Fidelity | GenomeWeb

This story has been updated from a previous version to include comments from New England Biolabs and to correct data regarding the synthetic base pair amplification.

By Ben Butkus

Scientists from Japan's Riken and spinout company TagCyx Biotechnologies have published research demonstrating a synthetic base pair system with high enough sensitivity, fidelity, and efficiency to be consistently used as an artificial third base pair for PCR amplification.

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