Q&A: Researchers Assess the Role of Amplicon Length in qPCR-based Detection of Cell-Free Fetal DNA | GenomeWeb

Real-time qPCR is commonly used to analyze cell-free fetal DNA in maternal serum and plasma for prenatal genetic screening, but this approach tends to detect very low fetal DNA concentrations — in the range of 1 percent to 3 percent early in pregnancy and 5 percent at term.

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