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Product Watch: Fluidigm's Single-Cell mRNA Seq Kits


Fluidigm this week introduced the mRNA sequencing application for its C1 Single-Cell Auto Prep System.

The new application enables transcriptome analysis of 96 single cells to rapidly study differential expression profiles of diverse cell populations. The C1 mRNA Seq kits and integrated fluidic circuits enable the processing of up to 96 single-cell cDNA libraries to quantify mRNA expression on Illumina sequencers.

The C1 system workflow requires as few as 200 cells, uses as little as 10 picograms per cell, and requires no reagent mixing, fragmentation, or purification. Researchers use Fluidigm's BioMark HD system to conduct routine quality control on the cDNA library before running it on an Illumina sequencer.

Fluidigm said that the protocol and reagent kits will be commercially available in January.

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.