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Product Watch: Akonni Biosystems and Sage Science

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Akonni Biosystems said this week that it has extended its family of TruTip extraction products for rapidly purifying human genomic DNA on the Hamilton Microlab Star line of robotic liquid handling workstations.

The first product provides laboratory technicians with the ability to process up to 300 µL of fresh or frozen whole blood. This kit can now also be used to process other sample types including buffy coat, tissue, buccal swabs, and cells, Akonni said. For all sample types, the kit delivers gDNA simultaneously from eight to 96 samples in less than 60 minutes.

The second TruTip gDNA kit supports the extraction and concentration of gDNA for up to 400 µL of saliva collected using the Oragene Discover collection kit from DNA Genotek, a subsidiary of OraSure Technologies. Given the non-invasive nature of collecting gDNA from saliva samples compared to blood, this sample type is commonly used for very large-scale genetic studies, such as for breast cancer research, Akonni said.

TruTip extraction kits running on the Hamilton Microlab Star system do not require a magnetic head, vacuum manifold, centrifuge, or other space-consuming or expensive capital equipment. Both TruTip gDNA kits can be used with a variety of analytical tools, including qPCR, real-time PCR, digital PCR, microarrays, and mid-multiplex bead-based systems, as well as traditional and next-generation sequencing systems.


Sage Science this week launched Pippin Link and Pippin Pulse, products designed to streamline library prep workflow and enhance the utility of the Pippin line of automated DNA size selection products.

Pippin Link is an accessory for the Pippin Prep and BluePippin that lets users boost throughput by connecting up to eight instruments and controlling them from a single computer, thus streamlining workflow and conserving bench space.

Pippin Pulse is a pulsed-field electrophoresis power supply for analytical gels. Based on the power supply of the BluePippin, Pippin Pulse is an affordable tool that lets researchers resolve DNA to 100 Kb and beyond. It uses a simple software interface that provides users full flexibility in developing their own field-inversion protocols, Sage Science said.

The Scan

Plan Rebuffed

The Associated Press reports China has rejected the World Health Organization's proposal to include the lab-leak theory in the next phase of its investigation into the origins of SARS-CoV-2.

Opossum Change

Researchers from Riken have used CRISPR to edit marsupial genomes, as Technology Review reports.

In the Ice

Cosmos magazine reports that researchers have uncovered more than two dozen ancient viruses in a Tibetan glacier.

Nature Papers Present Method to Uncover Differential RNA Modifications, Neutrophils in Innate Immune Response

In Nature this week: computational approach to identifying differential RNA modifications, and more.