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Product Watch: Oct 27, 2011

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GE Healthcare this week launched the Illustra ExoStar kit for enzymatic PCR and sequencing clean-up.

The kit provides researchers with a cost-effective product for enzymatic removal of unincorporated primers and nucleotides from PCR and sequencing reactions, with no degradation of target PCR products, GE said. The kit contains two enzymes designed to work together, with one tube of exonuclease 1 at a concentration of 10 enzyme units per µL; and one tube of Illustra alkaline phosphatase at a concentration of one enzyme unit per µL.

The Scan

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.

New Insights Into TP53-Driven Cancer

Researchers examine in Nature how TP53 mutations arise and spark tumor development.

Mapping Single-Cell Genomic, Transcriptomic Landscapes of Colorectal Cancer

In Genome Medicine, researchers present a map of single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer.

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.