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Product Watch: Oct 6, 2011

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Bio-Rad this week introduced its Precision Melt Supermix for high-resolution-melt-based detection of SNPs and CpG methylation for epigenetic studies.

The new reagents include EvaGreen dye, which is required for detection of class III/IV SNPs, Bio-Rad said. The supermix discriminates all four SNP classes across a broad range of amplicons, allowing the study of any genomic region, regardless of amplicon length and GC content.

The supermix is also fully compatible with bisulfite-converted DNA and allows for accurate detection of CpG methylation status, Bio-Rad said. In addition, its room temperature stability allows researchers to screen thousands of samples using Bio-Rad’s CFX96 Touch or CFX384 Touch real-time PCR systems, but the reagents are compatible with all HRM-capable thermal cyclers.


DuPont Qualicon this week introduced the BAX System STEC Suite, a trio of real-time PCR assays that enable food processors, reference labs, and government labs to detect Shiga toxin-producing Escherichia coli, or STEC, most commonly associated with severe foodborne illness.

The BAX System assay detects a combination of virulence genes called stx and eae to quickly and cost-effectively clear negative samples in production lines, DuPont said. Two multiplex PCR panels can determine which of the top six non-O157 STEC serogroups — O26, O45, O103, O111, O121, and O145 — are present in positive samples.

DuPont Qualicon said that it developed the tests in collaboration with the Agricultural Research Service of the US Department of Agriculture.

The Scan

Call to Look Again

More than a dozen researchers penned a letter in Science saying a previous investigation into the origin of SARS-CoV-2 did not give theories equal consideration.

Not Always Trusted

In a new poll, slightly more than half of US adults have a great deal or quite a lot of trust in the Centers for Disease Control and Prevention, the Hill reports.

Identified Decades Later

A genetic genealogy approach has identified "Christy Crystal Creek," the New York Times reports.

Science Papers Report on Splicing Enhancer, Point of Care Test for Sexual Transmitted Disease

In Science this week: a novel RNA structural element that acts as a splicing enhancer, and more.