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Product Watch: Oct 6, 2011


Bio-Rad this week introduced its Precision Melt Supermix for high-resolution-melt-based detection of SNPs and CpG methylation for epigenetic studies.

The new reagents include EvaGreen dye, which is required for detection of class III/IV SNPs, Bio-Rad said. The supermix discriminates all four SNP classes across a broad range of amplicons, allowing the study of any genomic region, regardless of amplicon length and GC content.

The supermix is also fully compatible with bisulfite-converted DNA and allows for accurate detection of CpG methylation status, Bio-Rad said. In addition, its room temperature stability allows researchers to screen thousands of samples using Bio-Rad’s CFX96 Touch or CFX384 Touch real-time PCR systems, but the reagents are compatible with all HRM-capable thermal cyclers.

DuPont Qualicon this week introduced the BAX System STEC Suite, a trio of real-time PCR assays that enable food processors, reference labs, and government labs to detect Shiga toxin-producing Escherichia coli, or STEC, most commonly associated with severe foodborne illness.

The BAX System assay detects a combination of virulence genes called stx and eae to quickly and cost-effectively clear negative samples in production lines, DuPont said. Two multiplex PCR panels can determine which of the top six non-O157 STEC serogroups — O26, O45, O103, O111, O121, and O145 — are present in positive samples.

DuPont Qualicon said that it developed the tests in collaboration with the Agricultural Research Service of the US Department of Agriculture.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more