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Product Watch: Dec 16, 2010

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Agilent Technologies said this week that its SureSelect Target Enrichment System now supports Roche-454 Life Sciences' next-generation sequencing platform.

The SureSelect system enables users to sequence only genomic regions of interest rather than entire genomes, and allows enrichment of targets ranging from smaller than 200 kb to more than 50 Mb in a single tube. The system also enables target enrichment of user-specified regions, the human kinome, the human X chromosome, and the human exome, Agilent said.

Agilent's SureSelect also supports the Illumina Genome Analyzer, Life Technologies' SOLiD 4, and HiSeq sequencing platforms.

Agilent also said this week that Gaithersburg, Md.-based EdgeBio has been appointed as a Certified Service Provider for SureSelect. Agilent said EdgeBio's SureSelect CSP status is specifically applicable to Life Technologies' SOLiD 4 system.


TriLink Biotechnologies this week launched CleanAmp 7-deaza-dGTP, a hot start solution for PCR amplification of problematic GC-rich sequences.

When DNA targets high in GC content are amplified, PCR product formation can often be compromised by inadequate strand separation and the propensity for complex secondary structure formation, TriLink said.

CleanAmp 7-deaza-dGTP is a fusion of the secondary structure-reducing nucleotide analog 7-deaza-dGTP and TriLink's CleanAmp dNTP Hot Start technology. The product is available individually for amplification of routine GC-rich targets or as the CleanAmp 7-deaza-dGTP Mix, which is recommended for more challenging targets with higher GC content, TriLink said.

The Scan

Not Yet a Permanent One

NPR says the lack of a permanent Food and Drug Administration commissioner has "flummoxed" public health officials.

Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.