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Product Watch: Nov 11, 2010

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IntegenX last week launched its Apollo 324 System, a benchtop robotic workstation that automates the construction of DNA fragment libraries for next-generation sequencing.

The Apollo 324 has an 8-tip pipette head with adjustable magnets and two Peltier heating/cooling units for PCR-type plates, and uses the proprietary BeadX In-Tip magnetic bead capture system to isolate and purify nucleic acids and automate end repair, A-tail addition, adapter ligation, and size selection. It can process from one to eight samples simultaneously, and can prepare eight libraries with amplification-ready products in less than four hours; or up to 24 libraries per day. Customized reagent kits optimize the performance of the system and are priced to significantly reduce the cost per reaction while ensuring accurate and consistent results, IntegenX said.

PrepX reagent kits are currently available for the Illumina Genome Analyzer and HiSeq 2000 next-generation sequencing systems.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.