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Product Watch : Sep 16, 2010

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Fluidigm has launched a reusable FR48.48 Dynamic Array integrated fluidic circuit, a reusable biochip for SNP genotyping. Each chip can be used up to five times and is able to produce results for 48 samples across 48 assays for a total of up to 11,520 genotypes over the five uses, Fluidigm said.

The company said that the reusable chip can decrease the cost per genotype by up to 80 percent for ultra-high throughput SNP genotyping customers when compared to its single-use 48.48 Dynamic Array IFC.

Fluidigm has also launched the IFC Controller WX, a device that automatically performs fast loading or cleaning of its reusable IFCs. According to the firm, the reusable FR48.48 chip can be loaded in 30 minutes and the overall time for loading and thermal cycling is about one hour, compared to approximately three hours for single-use 48.48 Dynamic Array IFCs.


Norgen Biotek has launched three new urine concentration, preservation, and isolation kits for preparing DNA, RNA, microRNA, and proteins from less than 1 mL to up to 30 mL of urine for applications such as PCR, RT-PCR, qPCR, qRT-PCR, and microarray analysis.

The kits contain a Urine Concentration and Preservation Device that the company said enables rapid and simple urine concentration without the use of centrifugation, as well as preservation of DNA, RNA, and proteins in urine samples at ambient temperature. The kit also includes a Urine Preservative that prevents the growth of bacteria and fungi and inactivates viruses.

Urine DNA, RNA, and proteins in preserved samples are stable for a year at room temperature, the company said.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.