IntegenX said this week that it has appointed David Smith as chief operating officer.

Smith most recently was executive vice president and CFO of Thoratec. Prior to joining Thoratec in 2006, Smith served as vice president and CFO of Chiron, which he joined in 1999 and held a number of positions of increasing responsibility. Smith has also worked for Anergen, Genentech, Syntex, and IBM.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.