The Association for Molecular Pathology's annual meeting, held in Long Beach, Calif., in October focused strongly on next-generation sequencing and its implementation in the clinic, especially for diagnosing, monitoring, and tailoring treatments for cancer.

However, a number of presentations made it clear that PCR and real-time PCR, while no longer the obvious technology choice for all molecular diagnostic and pathology applications, is still one of the most powerful tools available for infectious disease diagnostics and therapeutic monitoring.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.