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New England Biolabs to Distribute ArcticZymes' SAP Enzyme


ArcticZymes and New England Biolabs have signed a supply agreement for ArcticZymes' recombinant shrimp alkaline phosphatase, or SAP, enzyme.

Under the agreement, NEB, based in Ipswich, Mass., will offer the SAP enzyme through its global distribution network. The agreement also allows for the introduction of other ArcticZymes products through NEB at a later date. Financial terms of the pact were not disclosed.

ArcticZymes, a subsidiary of Biotec Pharmacon, is based in Tromsø, Norway, and specializes in cold-adapted and heat-labile enzymes for use in molecular biology and diagnostics. In January, it opened its first US office in the Philadelphia area (PCR Insider, 1/12/2012).

SAP is a DNA-modifying enzyme that can be completely heat-inactivated after 15 minutes at 65° C. As such, the enzyme is useful in applications such as PCR product clean-up and dephosphorylation prior to cloning, according to ArcticZymes' website.

The company's other products include cod uracil-DNA glycolase, or Cod UNG, and double-stranded-specific DNase, or dsDNase.

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