Johns Hopkins Team Develops TD-PCR Method to Detect Tandem Duplication Mutations in AML Patients | GenomeWeb

Clinical researchers from Johns Hopkins University School of Medicine have developed a technique called tandem duplication, or TD-PCR, for detecting internal tandem duplications of the FLT3 gene, which has been associated with a poor prognosis in acute myeloid leukemia patients

According to the researchers, the assay has a high degree of sensitivity and specificity, with a limit of detection approaching just a single mutant molecule, and as such may prove useful as a tool to monitor minimal residual disease in AML patients.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

In Science this week: genetic analysis of pollutant-tolerant fish, and more.

Researchers have found a rare carbapenem resistance gene on a US pig farm, NBC News reports.

New York officials are considering the use of a familial DNA search to get a lead on a suspect in the strangulation death of a runner.

NIH Director Francis Collins has selected a retired Army major general and cardiologist for the CEO spot at the agency's embattled Clinical Center.