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IP Watch: Thermo Fisher, Becton Dickinson, and Iquum Among Recent US Patent Awardees

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ABgene (Thermo Fisher) of Surrey, UK, has been awarded US Patent No. D679,830, "PCR multiwell plate."

Simon May, Jeffrey Coulling, Clive Harrison, and Nicola Burbidge are named as inventors.

The patent claim the ornamental design for a PCR multiwell plate, according to its abstract.


US Patent No. 8,415,141, "Enclosed unit for rapid detection of a target nucleic acid amplification product," has been awarded to an undisclosed party.

Qimin You, Lin Hu, Jiayong Gu, and Qinhao Yu, all of Hangzhou, China, are named as inventors.

Relates to a method for rapid detection of a target nucleic acid amplification product while preventing cross-contamination between target nucleic acid amplification products and avoiding false positives. The method comprises a) leaving the reaction tube unopened after the amplification reaction is finished, so as to prevent the target nucleic acid amplification product from leaking out and resulting in contamination; b) placing the unopened reaction tube inside an enclosed unit, enabling the target nucleic acid amplification product to be transferred to a test strip from the reaction tube in a physically enclosed environment; c) performing detection in a visual readout manner, and determining the result; d) discarding the enclosed unit in a safe place as a whole without opening it after the detection. The invention also relates to a totally enclosed unit for detecting a target nucleic acid amplification product, and further still relates to applications of the unit for the detection of infectious pathogens, food industry, agriculture, livestock husbandry, customs quarantine control, and determination of DNA.


US Patent No. 8,415,104, "Heat flow polymerase chain reaction systems and methods," has been awarded to an undisclosed party.

Warren Dinges of Seattle is named as inventor. Dinges is CEO, president, and founder of startup company Heatflow Technologies, and a physician specializing in infectious diseases at the Polyclinic.

The patent covers methods and systems for PCR that are capable of detecting amplified DNA during or after the PCR process. The methods and systems may utilize differential scanning calorimetry or differential thermal analysis techniques.


HandyLab (Becton Dickinson) has been awarded US Patent No. 8,415,103, "Microfluidic cartridge."

Kalyan Handique is named as inventor.

Relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate comprising a plurality of sample lanes, each of which comprises a microfluidic network having, in fluid communication with one another: an inlet; a first valve and a second valve; a first channel leading from the inlet, via the first valve, to a reaction chamber; and a second channel leading from the reaction chamber, via the second valve, to a vent.


Iquum has been awarded US Patent No. 8,414,845, "Sample multiprocessing."

Shuqi Chen, Bertrand Lemieux, and Lingjun Shen are named as inventors.

Describes a sample processing vessel that may include a branch segment and at least two tracks. The tracks may be fluidly isolated from one another by a permanent seal, and may be segmented by breakable seals. The branch segment may be temporarily isolated from the tracks by breakable seals and put in fluid communication with the tracks once those seals are broken, such that fluid received by the branch segment is divided into portions that pass into both tracks; wherein at least one segment in the first track contains a reagent selected to perform a first assay; at least one segment in said second track contains a reagent selected to perform a second assay; and at least one segment not in said first or second tracks contains a reagent to prepare a sample for said first and second assays.

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