Applied Biosystems (Life Technologies) has been awarded US Patent No. 7,943,752, "Modified oligonucleotides and applications thereof."

Khairuzzaman Mullah, Zhaochun Ma, and Wanli Bi are named as inventors on the patent.

The patent discloses, among other things, primers containing certain modified nucleobases in their 3' terminal region that provide reduced formation of primer-dimers during amplification reactions, and various methods of use thereof.

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