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IP Watch: Recent Patents Related to PCR, Nucleic Acid Amplification, and Sample Prep: Sep 9, 2010

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DuPont has been awarded US Patent No. 7,790,876, "Sequences diagnostic for foot and mouth disease."

Richard Ebersole, Linda DeCarolis, and Raymond Jackson are named as inventors on the patent.

Provides methods and materials for detecting the foot and mouth disease virus. The methods may utilize PCR amplification, with or without an internal positive control, and appropriate primer pairs. The reagents to perform these methods can be supplied as a kit and/or in tablet form.


The Mayo Foundation for Medical Research and Roche Molecular Systems have been awarded US Patent No. 7,790,875, "Detection of group B streptococcus."

James Uhl, Franklin, Cockerill, Christian Aichinger, and Astrid Reiser are named as inventors on the patent.

Provides methods, primers and probes, and articles of manufacture containing such primers and probes to detect group B streptococcus in biological samples using real-time PCR.


Qiagen has been awarded US Patent No. 7,790,865, "Eluting reagents, methods, and kits for isolating DNA."

Ellen Heath and Ruth Shuman are named as inventors on the patent.

Provides eluting reagents and methods for isolating DNA from biological materials.


Olink has been awarded US Patent No. 7,790,388, "Nucleic acid amplification method."

Ulf Landegren, Mats Gullberg, and Mats Nillson are named as inventors on the patent.

Describes a nucleic acid amplification method and probes for use within the method.


Siemens Healthcare Diagnostics has been awarded US Patent No. 7,790,386, "Neisseria gonorrhoeae-specific oligonucleotide sequences."

Lailing Ku, Charlene Donovan-Bush, David Sherman, and Qi Meng are named as inventors on the patent.

Relates to oligonucleotide sequences for amplification primers and detection probes and their use in nucleic acid amplification methods for the selective and specific detection of Neisseria gonorrhoeae in biological samples. The invention also provides oligonucleotide primer sets and primer/probe sets in the form of kits for the detection and diagnosis of gonococcal infection. The inventive oligonucleotide primers and probes can also be used in combination with other specific oligonucleotide primers and probe for the simultaneous detection of Neisseria gonorrhoeae and other target organisms, such as Chlamydia trachomatis.


Sungkyunkwan University has been awarded US Patent No. 7,790,375, "Primer for detection of human papillomavirus."

Joo-Sung Yang and Hyeran Cha are named as inventors on the patent.

Discloses primers specific to the genome of HPV genotypes 11, 16, 18, and 31. Also discloses a kit for detecting the HPV genome comprising the primers and a method of detecting the HPV genome using the primers.


Hitachi has been awarded US Patent No. 7,790,368, "Method for analyzing nucleic acid."

Shinichi Fukuzono is the sole inventor named on the patent.

Provides a method for analyzing nucleic acid comprising the steps of extracting, amplifying, and detecting the nucleic acid of interest. One or more internal control nucleic acids, which can be detected and discriminated from the nucleic acid of interest, are added to a sample prior to the performance of each step, and the success or failure of each step is judged from the detection results obtained for the respective internal control nucleic acids in the detection step. The internal control nucleic acids added prior to each step can be discriminated from each other.

The Scan

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