Johns Hopkins University has been awarded US Patent No. 8,288,524, "Molecular diagnosis of bacteremia."
Richard Rothman, Maulik Majmudar, and Charlotte Gayos are named as inventors.
Describes a highly specific assay that can be used to detect bacteremia in the clinical setting. The ubiquitous background endogenous DNA present in all PCR reagents is eliminated using a restriction endonuclease digestion. Universal primers for eubacteria are used for detection, and specific primers or probes for bacterial species can be used to identify species.