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IP Watch: Hologic, Illumina, Roche, Others Win US Patents

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The Penn State Research Foundation has been awarded US Patent No. 8,759,000, "Methods for nucleic acid manipulation."

Stephen Benkovic and Frank Salinas are named as inventors.


Gen-Probe (Hologic) has been awarded US Patent No. 8,759,003, "Detection of West Nile virus nucleic acids in the viral 3' non-coding region."

Jeffrey Linnen and Reinhold Pollner are named as inventors.


Illumina has been awarded US Patent No. 8,759,037, "Amplification methods to minimize sequence specific bias."

Roberto Rigatti, Jonathan Boutell, and Min-Jui Shen are named as inventors.

Illumina was also awarded US Patent No. 8,759,038, "Compositions and methods for sequencing nucleic acids."

Roberto Rigatti, Jonathan Boutell, Jason Betley, and Niall Gormley are named as inventors.


Rheinische Friedrich-Wilhelms-Universitaet Bonn has been awarded US Patent No. 8,759,061, "Mutated DNA polymerases with increased mispairing discrimination."

Andreas Marx, Daniel Summerer, and Nicolas Rudinger are named as inventors.


Roche has been awarded US Patent No. 8,759,063, "DNA polymerases with improved activity."

Keith Bauer, Thomas Myers, and Shawn Suko are named as inventors.


Lawrence Livermore National Security has been awarded US Patent No. 8,762,068, "Methods for threshold determination in multiplexed assays."

Lance Tammero, John Dzenitis, and Benjamin Hindson are named as inventors.

The Scan

Looking for Omicron

NPR reports that SARS-CoV-2 testing in the US has gotten better but also that some experts say more needs to be done to better track the Omicron variant.

Holmes Alleges Abuse

The Associated Press reports that Theranos' Elizabeth Holmes has testified at her wire fraud trial that her business and romantic partner abused her.

Bit More Diverse, But More to Do

While Black and Hispanic patients are more likely to participate in cancer clinical trials than previously, they are still underrepresented, according to US News & World Report.

PNAS Papers on Yeast Gene Silencing, Zika Virus Inhibition, Immunoglobulin Hypermutation

In PNAS this week: gene silencing in Saccharomyces cerevisiae, possible neuroprotective role for SHFL in a mouse model of Zika virus infection, and more.