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IP Watch: Hologic, Illumina, Roche, Others Win US Patents

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The Penn State Research Foundation has been awarded US Patent No. 8,759,000, "Methods for nucleic acid manipulation."

Stephen Benkovic and Frank Salinas are named as inventors.


Gen-Probe (Hologic) has been awarded US Patent No. 8,759,003, "Detection of West Nile virus nucleic acids in the viral 3' non-coding region."

Jeffrey Linnen and Reinhold Pollner are named as inventors.


Illumina has been awarded US Patent No. 8,759,037, "Amplification methods to minimize sequence specific bias."

Roberto Rigatti, Jonathan Boutell, and Min-Jui Shen are named as inventors.

Illumina was also awarded US Patent No. 8,759,038, "Compositions and methods for sequencing nucleic acids."

Roberto Rigatti, Jonathan Boutell, Jason Betley, and Niall Gormley are named as inventors.


Rheinische Friedrich-Wilhelms-Universitaet Bonn has been awarded US Patent No. 8,759,061, "Mutated DNA polymerases with increased mispairing discrimination."

Andreas Marx, Daniel Summerer, and Nicolas Rudinger are named as inventors.


Roche has been awarded US Patent No. 8,759,063, "DNA polymerases with improved activity."

Keith Bauer, Thomas Myers, and Shawn Suko are named as inventors.


Lawrence Livermore National Security has been awarded US Patent No. 8,762,068, "Methods for threshold determination in multiplexed assays."

Lance Tammero, John Dzenitis, and Benjamin Hindson are named as inventors.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.