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IP Watch: Diagnoplex, BioMérieux, Fluidigm, Quest, Others Win US Patents

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The Regents of the University of California have been awarded US Patent No. 8,697,348, "Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571."

Charles Sawyers, Mercedes Gorre, Neil Shah, and John Nicoll are named as inventors.


Diagnoplex has been awarded US Patent No. 8,697,350, "Biomarker combinations for colorectal cancer."

Curzio Ruegg, Sylvain Monnier-Benoit, Laura Ciarloni, and Stavros Therianos are named as inventors.


BioMérieux has been awarded US Patent No. 8,697,352, " Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of HIV-1."

Jaap Goudsmit, Pieter Oudshoorn, Suzanne Jurriaans, and Vladimir Lukashov are named as inventors.


Japan Advanced Institute of Science and Technology has been awarded US Patent No. 8,697,357, "Method for detection of methylcytosine using photoresponsive probe."

Kenzo Fujimoto, Masayuki Ogino, and Yuta Taya are named as inventors.


Technische Universitaet Dresden has been awarded US Patent No. 8,697,358, "Non-invasive method for diagnosis of prostate cancer."

Manfred Wirth, Susanne Fuessel, and Rainer Koch are named as inventors.


Caliper Life Sciences (PerkinElmer) has been awarded US Patent No. 8,697,362, "Methods of detecting low copy nucleic acids."

Michael Knapp, Jill Baker, Andrea Chow, Anne Kopf-Sill, and Michael Spaid are named as inventors.


Fluidigm has been awarded US Patent No. 8,697,363, "Methods for detecting multiple target nucleic acids in multiple samples by use nucleotide tags."

Alain Mir, Ramesh Ramakrishnan, Marc Unger, and Bernhard Zimmermann are named as inventors.


Quest Diagnostics and US Genomics have been awarded US Patent No. 8,697,399, "Nucleic acid size detection method."

Donghui Huang, Charles Strom, Steven Potts, and Jenny Rooke are named as inventors.


Shimadzu Corporation has been awarded US Patent No. 8,697,400, "Method for amplification of DNA from blood sample and DNA amplification kit therefor."

Masamitsu Shikata is named as the inventor.


New England Biolabs has been awarded US Patent No. 8,697,408, "Ligation enhancement."

Rebecca Kucera and Thomas Evans, Jr. are named as inventors.


ZS Genetics has been awarded US Patent No. 8,697,432, "Systems and methods of analyzing nucleic acid polymers and related components."

William Glover, III is named as the inventor.


Samsung has been awarded US Patent No. 8,697,433, "Polymerase chain reaction module and multiple PCR system using the same."

Kwang-wook Oh, Jin-tae Kim, Kak Namkoong, Chin-sung Park, and Yoon-kyoung Cho are named as inventors.


E. I. du Pont de Nemours and Company has been awarded US Patent No. 8,697,852, "Genetic fingerprinting and identification method."

Frank Burns and Xuan Peng are named as inventors.


The President and Fellows of Harvard College have been awarded US Patent No. 8,698,481, "High-resolution molecular sensor."

Charles Lieber, Qihua Xiong, Ping Xie, and Ying Fang are named as inventors.


Koninklijke Philips has been awarded US Patent No. 8,700,381, "Methods for nucleic acid quantification."

Josephus Kahlman, Bin Yin, and Tamara Nijsen are named as inventors.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.