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IP Watch: Abbott, DNAForm, Riken, Mayo, Roche, Gen-Probe Among US Patent Winners

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Abbott Laboratories has been awarded US Patent No. 8,099,243, "Methods for quantifying a concentration of a target nucleic acid."

Eric Shain, John Clemens, Tzyy-Wen Jeng, and George Schneider are named as inventors on the patent.

Describes a method and system for determining the quantity of an analyte initially present in a chemical and/or biological reaction; as well as a computer-implemented method and system to automate portions of the analysis comprising mathematical or graphical analysis of an amplification reaction.

In addition, Ibis Biosciences, now part of Abbott Laboratories, has been awarded US Patent No. 8,097,416, "Methods for identification of sepsis-causing bacteria."

Thomas Hall, Rangarajan Sampath, Vanessa Harpin, Steven Hofstadler, and Yun Jiang are named as inventors on the patent.

Provides compositions, kits, and methods for rapidly identifying and quantifying sepsis-causing bacteria by molecular mass and base composition analysis.


Longhorn Vaccines and Diagnostics has been awarded US Patent No. 8,097,419, "Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009."

Gerald Fischer and Luke Daum are named as inventors on the patent.

Discloses oligonucleotide amplification primers and detection probes specific for amplifying and detecting pathogenic organisms including, for example, specific influenza A H1N1 viral isolates. Also discloses a biological organism identification kit including the disclosed nucleic acid probes and primers, as well as thermal cycling reagents. The kit is both portable and durable, and may also be self-contained for remote or in-field analysis and identification of particular influenza isolates from a variety of biological specimen types, the patent's abstract states.


DNAForm and Riken have been awarded US Patent No. 8,097,414, "Method for detecting and amplifying nucleic acid."

Yoshihide Hayashizaki, Yasumasa Mitani, and Yuki Kawai are named as inventors on the patent.

Provides a method for detecting and/or amplifying a nucleic acid contained in a biological sample such as blood or cells. The method comprises the steps of adding to a sample at least one substance selected from the group consisting of polyphenols, polyhydric alcohols, sugar acids, sugar alcohols, and hydrophilic biodegradable polymers; complementarily binding an oligonucleotide complementary to a part of the sequence of a nucleic acid to be detected; and detecting the nucleic acid.


The Mayo Foundation for Medical Education and Research and Roche Molecular Systems have been awarded US Patent No. 8,097,413, "Detection of Group B Streptococcus."

James Uhl, Franklin Cockerill, Christian Aichinger, and Astrid Reiser are named as inventors on the patent.

Provides methods to detect Group B Streptococcus in biological samples using real-time PCR. Specifically, the patent provides primers and probes for detecting GBS and articles of manufacture containing such primers and probes for detecting GBS.


Gen-Probe has been awarded US Patent No. 8,097,409, "Kits for detecting Group B Streptococci."

Reinhold Pollner and Edgar Kamantigue are named as inventors on the patent.

Provides compositions, methods, and kits to detect Group B Streptococci. In particularly, the patent describes oligonucleotides that are useful as amplification primers and hybridization probes to detect very low levels of GBS nucleic acids.


STMicroelectronics has been awarded US Patent No. 8,097,222, "Microfluidic device with integrated micropump, in particular biochemical microreactor, and manufacturing method thereof."

Mario Scurati is named as inventor on the patent.

Describes a microfluidic device for nucleic acid analysis. The device includes a monolithic semiconductor body; a microfluidic circuit at least partially accommodated in the monolithic semiconductor body; and a micropump. The microfluidic circuit includes a sample preparation channel formed on the monolithic semiconductor body and at least one microfluidic channel buried in the monolithic semiconductor body. The micropump includes a plurality of sealed chambers with respective openable sealing elements and having a first pressure therein that is different from a second pressure in the microfluidic circuit. In addition, the micropump and the microfluidic circuit are configured so that opening the openable sealing elements provides fluidic coupling between the respective chambers and the microfluidic circuit. The openable sealing elements are integrated in the monolithic semiconductor body.

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