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IP Update: Recent Patents Related to PCR, Sample Prep, and Nucleic Acid Amplification: Mar 9, 2010


US Patent No. 7,674,582. Methods for amplification monitoring and gene expression profiling involving real-time amplification reaction sampling.

Inventor: Vladimir Slepnev

Assignee: PrimeraDx

Relates to methods of monitoring the amplification of one or more nucleic acid sequences of interest, particularly in real time. The patent provides methods for monitoring the amplification of one sequence or two or more sequences from a single sample, as well as methods for monitoring the amplification of one or more sequences from two or more samples. The monitoring methods permit improved determination of the abundance of one or more target nucleic acids, especially target RNA species, in one or more original samples.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.