US Patent No. 7,651,839. Method of optimizing amplification in PCR. Inventors: Haikuo Li, Jiehuan Huang, Junhong Lv, Xiaodong Zhang, Jun Hu, Zhizhou Zhang, Chunhai Fan. Assignee: Shanghai Jiao Tong University.
Describes a method for optimizing PCR amplification by adding elementary substance material into the PCR system. The elementary substance material is selected from a group comprising titanium nickel, bismuth, stibium, selenium, chromium, or a mixture. The method is more effective than conventional amplification methods, and could be particularly useful in applications such as multiplex PCR, two-round PCR, low-copy PCR, long-term PCR, and rapid PCR, according to the patent's abstract.