Skip to main content
Premium Trial:

Request an Annual Quote

Health Canada Approves Hologic's Aptima HPV Assay for Panther Platform

NEW YORK (GenomeWeb News) – Health Canada has approved Hologic's Aptima HPV assay for use on the Panther system, the company said on Thursday.

The test is performed with Hologic's ThinPrep liquid cytology specimen and can be used before or after it has been processed for cytology testing on the ThinPrep 2000 system. The mRNA-based assay is a nucleic acid amplified test for detecting 14 high-risk strains of human papillomavirus associated with cervical cancer and precancerous lesions.

According to Hologic, the test has demonstrated "significantly improved specificity with no compromise in disease detection."

The Aptima HPV assay is for the detection of mRNA overexpressed from the E6 and E7 viral oncogenes in 14 high-risk HPV types and was approved for two uses. One is the screening of women at least 21 years of age with atypical squamous cells of undetermined significance cervical cytology results for determining whether a patient should be referred to colposcopy.

It also was approved for use as an adjunct with cervical cytology to screen women at least 30 years of age to evaluate for the presence or absence of high-risk HPV types.

The US Food and Drug Administration approved the test for Panther in July. Canada approved the test for use on Hologic's Tigris platform in April.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.