German Team Details RT-qPCR Assay to Detect ALK Rearrangements from FFPE | GenomeWeb

A team of researchers in Germany has developed a new assay to help determine which non-small cell lung cancers are likely to respond to certain targeted therapies.

As a screen for gene rearrangements, the assay uses quantitative reverse transcription-PCR to show altered ratios of 3' to 5' ends of the aplastic lymphoma tyrosine kinase, or ALK gene, rather than specific mutations. It is also optimized to work on formalin-fixed paraffin-embedded tissue samples.

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In PNAS this week: statistical approach to examine intra-tumor heterogeneity, new genetic condition called otulipenia, and more.

Blood tests looking for biomarker changes could catch mental illnesses earlier, Newsweek reports.

DNA testing offers Korean adoptees a way to find their birth parents that sidesteps bureaucratic red tape, according to the New York Times.

A National Institutes of Health researcher has filed an Equal Employment Opportunity complaint against the agency, the Washington Post reports.