A team comprising researchers from Genomic Health and the Cleveland Clinic have published a study describing the analytical validation of Oncotype DX prostate, the company's RT-PCR-based gene expression assay intended to predict prostate cancer aggressiveness and severity from fine-needle biopsies to help guide treatment decisions for men with early-stage disease.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.