Skip to main content
Premium Trial:

Request an Annual Quote

Fluidigm Launches Early Access Program for SNP Genotyping Platform

NEW YORK (GenomeWeb) — Fluidigm said today that it has launched an early access program for its new SNP genotyping platform, the Juno system, for its key production genomics customers and prospects.

Juno is a sample prep engine for SNP genotyping that allows scientists to genotype low-concentration DNA samples from tissue, buccal swabs, formalin-fixed paraffin-embedded samples, and polyploidy organisms in less than three hours, Fluidigm said.

Traditionally, SNP genotyping requires high-concentration and -quality samples, and substantial amounts of reagents, resulting in high operating costs, the company added. These requirements have hampered the practical use of low-concentration DNA samples, such as buccal swabs and FFPE, in production genomics.

The Juno system uses an integrated fluidic circuit that incorporates pre-amplification and genotyping of up to 96 samples and 96 assays on a single chip. The system also requires as little as 5.5 nanograms of DNA at a concentration of 2.5 nanograms per microliter of sample, the company said.

Fluidigm is also releasing new master mix chemistries that combine all of the reagents need to perform integrated genotyping on the Juno system.

Targeted uses for the Juno system include sample identification, quality control, and DNA fingerprinting by biobanking and cell culture facilities, and integrated on-chip pre-amplification and genotyping analysis by Ag-Bio customers, Fluidigm said.

"Our production genomics customers commonly struggle with highly variable or low-concentration samples, whether they come from a buccal swab, a needle biopsy, a seed, or a biobank. Juno is an answer to this challenge," CEO Gajus Worthington said in a statement.

The company hasn't yet named any participants in the early access program for the Juno system.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.