Scientists from Arizona State University's Biodesign Institute are using a two-year, approximately $420,000 grant from the National Institutes of Health to further develop a tool that combines laser-based excision and ablation with emulsion-based droplet PCR to profile mRNA expression in single cells.

Once developed, the platform could provide life science researchers with a tool to better elucidate cellular heterogeneity in, for instance, cancerous tissue, by maintaining spatial and temporal resolution of gene expression in single cells.

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