Abbott, GSK to Develop PCR-Based Molecular Dx to Select Patients for Trial Skin Cancer Therapy | GenomeWeb

Abbott said today that it has signed a pact with GlaxoSmithKline to develop a PCR-based molecular diagnostic test for a specific biomarker to aid in selecting patients who may benefit from an immunotherapy under development at GSK.

The agreement builds on a partnership between the companies announced last year to develop a PCR test for the same protein biomarker — MAGE-A3 — to screen for non-small-cell lung cancer patients eligible to receive GSK's developmental NSCLC therapy, called MAGE-A3 Antigen-Specific Cancer Immunotherapeutic, or MAGE-A3 ASCI.

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In Nucleic Acids Research this week: personal genome approach to RNA-seq read alignment, hematopoietic Systems Biology Repository, and more.

A man is using DNA evidence to argue that he is the rightful heir to the baronetcy of Stichill, the Guardian reports.

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