Study Claims PCR from Primers Annealed in Parallel Orientation

Feb 06, 2015

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NEW YORK (GenomeWeb) – Researchers in India claim to have accomplished replication of DNA in a parallel orientation, challenging the dogma that PCR can only be initiated when primers are aligned in an anti-parallel way

In a study published ahead of peer review in the online journal F1000 Research, the scientists described how they accomplished parallel DNA PCR, or PD-PCR, using single-stranded template DNA and Taq Polymerase.

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