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Product Watch: Mo Bio PowerMag; SeraCare AccuSpan; Biosearch qPCR Design Lab

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Mo Bio Laboratories has launched the PowerMag Blood DNA/RNA Isolation Kit.

The new kit is designed for automated purification of nucleic acids from blood samples using the Thermo Fisher Scientific KingFisher automated processing system and other similar automation platforms. The kits work with all types of blood samples, including fresh and frozen whole blood, buffy coat, plasma, and stabilized blood. They also feature the company's ClearMag magnetic particle technology, which captures DNA and RNA without binding common blood-derived PCR inhibitors, Mo Bio said.


SeraCare Life Sciences this week introduced seven new AccuSpan molecular linearity panels for the detection of adenovirus, varicella-zoster virus, JC virus, herpes simplex viruses 1 and 2, Epstein-Barr virus, and BK virus.

The new panels help assay developers challenge their transplant assays from extraction phase through amplification. Each panel comprises one negative, one low positive, one medium positive, and one high positive sample. The panels come in a ready-to-use format with target concentrations covering the dynamic range of most molecular assays, SeraCare said.


Biosearch Technologies this week introduced qPCR Design Lab, a comprehensive website for assay design, oligo analysis, webinars, and references.

Visitors to qPCR Design Lab can quickly perform common dilution and resuspension calculations with an oligo toolbox or determine physical properties of an oligo with the OligoSpec calculator. Users can also visualize combinations of fluorophore absorption and emission spectra with the Spectral Overlay Tool for multiplexed qPCR, and can obtain reporter dye and quencher recommendations specific to their real-time PCR instruments.

The lab also allows users to design assays with RealTimeDesign software for qPCR applications including gene expression analysis, SNP genotyping, and multiplexed qPCR. Finally, the site features educational animations and webinars that allow visitors to stay up to date with best practices in assay design or learn more about MIQE guidelines, Biosearch said.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.