Skip to main content
Premium Trial:

Request an Annual Quote

Product Watch: Exiqon's microRNA qPCR Panels for Stem Cells

Premium

Exiqon this week launched Stem Cell Focus microRNA PCR panels for embryonic and induced pluripotent stem cell research.

The 85 qPCR and 11 control assays have been experimentally optimized and validated to fit the needs of researchers interested in differentiation, proliferation, development, and homeostasis of stem cells.

The assays require a 10 µl reaction volume and sample input of as little as 1 picogram of total RNA without any need for pre-amplification. The assays can detect as few as five copies of microRNAs, and can detect microRNAs with high A-T sequence content due to the inclusion of the company's Locked Nucleic Acid, or LNA, technology in the PCR primers.

The new PCR panels can be used on all major brands of qPCR instruments, including instruments with both 96- and 384-well array formats, Exiqon said.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.