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Product Watch: Mar 17, 2011

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Exiqon this week launched 235 additional pre-validated miRcury LNA Universal RT microRNA qPCR assays for sensitive and specific quantification of miRNAs.

With the launch, Exiqon now offers 1,731 pre-validated qPCR assays for human, mouse, and rat miRNAs. In addition, Exiqon offers custom-designed LNA-enhanced qPCR assays for any miRNA.


Bio-Rad this week introduced CFX Manager 2.0, real-time PCR experiment setup and data-analysis software for use with the company's CFX96, CFX384, and MiniOpticon real-time PCR systems.

Combined with Biogazelle's qbasePlus software, which is included with the CFX96 and CFX384 systems, CFX Manager 2.0 enhances researchers' ability to comply with the emerging standard, minimum information for publication of quantitative real-time PCR experiments, or MIQE.

CFX Manager's terminology is consistent with MIQE guidelines, and data can be exported in the recommended RDML file format for submission with a manuscript or for import into qbasePLUS software.

CFX Manager 2.0 also features Scheduler Streamline experiment setup; Master Mix Calculator, Custom Data View, and Custom Data Export.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.