NEW YORK (GenomeWeb) – The global burden of soil-transmitted helminths (STHs) may be decreasing due to large-scale treatment programs, but improved diagnostics are needed to support eradication efforts.
Scientists at Smith College have now developed a pipeline using next-generation sequencing and a Galaxy-based web server called RepeatExplorer to uncover non-coding repetitive sequences in five species of STH and develop a qPCR assay with improved specificity and sensitivity.