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NGS-Based Pipeline Used to Develop Improved Parasitic Worm MDx

Apr 06, 2016
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Madeleine Johnson
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NEW YORK (GenomeWeb) – The global burden of soil-transmitted helminths (STHs) may be decreasing due to large-scale treatment programs, but improved diagnostics are needed to support eradication efforts.

Scientists at Smith College have now developed a pipeline using next-generation sequencing and a Galaxy-based web server called RepeatExplorer to uncover non-coding repetitive sequences in five species of STH and develop a qPCR assay with improved specificity and sensitivity.

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