New Method Pairs Artificial Nucleotide, Mutant Polymerase to Detect DNA Adducts

Jan 21, 2015

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NEW YORK (GenomeWeb) – Alkylating substances such as tobacco smoke and environmental toxins can create mutagenic alkylguanine DNA adducts. This type of DNA damage is often a first step in carcinogenesis, but information on these rare, site-specific modifications is hard to come by.

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