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IP Watch: Sequenom, Qiagen, Asuragen, Affymetrix, Johns Hopkins, Others Win US Patents

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Vertex Pharmaceuticals has been awarded US Patent No. 8,679,740, "Methods for amplifying hepatitis C virus nucleic acids."

Ann Kwong, James Frantz, Douglas Bartels, Chao Lin, Benjamin Shames, Sheila Seepersaud, Judith Lippke, Tara Kieffer, Yi Zhou, Eileen Zhang, and James Sullivan are named as inventors.


Sequenom has been awarded US Patent No. 8,679,741, "Methods and compositions for the extraction and amplification of nucleic acid from a sample."

Carolyn Hoyal-Wrightson, Andreas Braun, and Karsten Schmidt are named as inventors.


Qiagen has been awarded US Patent No. 8,679,744, "Method for cleaning and isolating nucleic acid using ammonium or phosphonium cationic detergents."

Thorsten Singer is named as the inventor.


Epigenomics AG has been awarded US Patent No. 8,679,745, "Method for providing DNA fragments derived from an archived sample."

Matthias Ballhause, Kurt Berlin, Dimo Dietrich, Antje Lukas, Matthias Schuster, Ute Wagner, Reinhold Wasserkort, and Heike Ziebarth are named as inventors.


Infraegis has been awarded US Patent No. 8,679,752, "Compositions and methods for detecting food-borne pathogens."

Robert Levin is named as the inventor.


Asuragen has been awarded US Patent No. 8,679,757, "PCR methods for characterizing the 5' untranslated region of the FMR1 and FMR2 genes."

Gary Latham, Liangjing Chen, and Sachin Sah are named as inventors.


Affymetrix has been awarded US Patent No. 8,679,758, "Complexity management of genomic DNA."

Hajime Matsuzaki, Xing Su, Sean Walsh, Giulia Kennedy, and Rui Mei are named as inventors.


The Johns Hopkins University has been awarded US Patent No. 8,679,788, "Methods for the detection of nucleic acid differences."

James Eshleman, Chanjuan Shi, and Susan Eshleman are named as inventors.


The Chinese University of Hong Kong has been awarded US Patent No. 8,680,255, "Detection of HBX/8P11 hybrid sequence in human hepatocellular carcinoma."

Nathalie Wong is named as the inventor.


US Patent No. 8,680,257, "Kits for comparative transcript analysis and mutant sequence enrichment," has been awarded to an unspecified entity.

Ming-Sheng Lee, Chung-Han Lee, and Jeffery Lee are named as inventors.


US Patent No. 8,680,261, "Methods for purifying nucleic acids," has been awarded to an unspecified entity.

Robert Bridenbaugh, Warren Dang, and Lee Bussey are named as inventors.


Natera has been awarded US Patent No. 8,682,592, "System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals."

Matthew Rabinowitz, Milena Banjevic, Zachary Demko, and David Johnson are named as inventors.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.