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IP Watch: Roche, Sequenom, Illumina, 3M, Others Win US Patents

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Roche has been awarded US Patent No. 8,652,811, "Dry composition of reaction compounds with stabilized polymerase."

Thomas Metzler, Tobias Haslinger, Annette Peceny, and Harald Sobek are named as inventors.

Roche has also been awarded US Patent No. 8,652,775, "Alkyl amines improve detection of components of formaldehyde-fixed biological samples."

Stephen Will, Veeraiah Bodepudi, Ellen Fiss, and Rachel Shahinian are named as inventors.


Sequenom has been awarded US Patent No. 8,652,780, "Restriction endonuclease enhanced polymorphic sequence detection."

Mathias Ehrich and Dirk Van den Boom are named as inventors.


Genisphere has been awarded US Patent No. 8,653,251, "Methods and kits for nucleic acid amplification."

Robert Getts, James Kadushin, and Kelly Sensinger are named as inventors.


3M Innovative Properties has been awarded US Patent No. 8,652,812, "Dual oligonucleotide method of nucleic acid detection."

Jesse Miller is named as the inventor.


Illumina has been awarded US Patent No. 8,652,810, "Methods of nucleic acid amplification and sequencing."

Celine Adessi, Eric Kawashima, Pascal Mayer, Jean-Jacques Mermod, and Gerardo Turcatti are named as inventors.


Longhorn Vaccines & Diagnostics has been awarded US Patent No. 8,652,782, "Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids."

Gerald Fischer and Luke Daum are named as inventors.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.