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IP Watch: Roche, Life Tech, Pacific Biosciences, Promega, Others Win US Patents

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Roche has been awarded US Patent No. 8,658,109, "Use of a bis-maleic anhydride cross-linking agent for fixation of a cell or tissue sample."

Hans-Peter Josel, Michael Gerg, Rupert Hermann, and Rosa Diaz are named as inventors.

Roche has also been awarded US Patent No. 8,658,366, "Detection of target variants using a fluorescent label and a soluble quencher."

Stephen Will, Amar Gupta, and Laura Geyer are named as inventors.


Becton Dickinson has been awarded US Patent No. 8,658,397, "Assay for detecting closely-related serotypes of human papillomavirus (HPV)."

Chi Chen, Hugh Peck, Michael Porter, Gregory Richart, and Ray McMillian are named as inventors.


Applied Biosystems (Life Technologies) has been awarded US Patent No. 8,658,093, "Devices and methods for the detection of analytes."

Aldrich Lau, Robert Eason, Kristian Scaboo, and Handong Li are named as inventors.


OTC Biotechnologies has been awarded US Patent No. 8,658,613, "Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health."

John Bruno is named as the inventor.


Pacific Biosciences has been awarded US Patent No. 8,658,365, "Nucleic acid synthesis compositions and methods and systems for using same."

Keith Bjornson, Harold Lee, and Jonas Korlach are named as inventors.

Pacific Biosciences has also been awarded US Patent No. 8,658,364, "Isolation of polymerase-nucleic acid complexes."

Thang Pham, Arunashree Bhamidipati, Kevin Travers, Eric Olivares, Tyson Clark, and Jonas Korlach are named as inventors.


Promega has been awarded US Patent No. 8,658,360, "Nucleic acid purification with a binding matrix."

Rex Bitner, Michelle Mandreker, and Paula Brisco are named as inventors.


Samsung has been awarded US Patent No. 8,658,359, "Method and apparatus for disrupting cells and purifying nucleic acid using a single chip."

In-ho Lee, Jun-hong Min, Young-rok Kim, Jae-ho You, Chang-eun Yoo, Jeong-gun Lee, and Ki-woong Han are named as inventors.


Life Technologies has been awarded US Patent No. 8,658,776, "Synthesis of 2',3'-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization."

Zhaochun Ma, Khairuzzaman Mullah, and Robert Eason are named as inventors.


Qiagen has been awarded US Patent No. 8,658,417, "Multiple-input analytical system."

James Godsey, Emmett Brown, Jay Srinivasan, Bandele Jeffrey-Coker, and Jon Willoughby are named as inventors.


Euclid Diagnostics has been awarded US Patent No. 8,658,369, "Methods for evaluating the methylation status of a polynucleotide."

Wadiha Freije and Igor Brikun are named as inventors.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.