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IP Watch: Roche, Life Tech, Pacific Biosciences, Promega, Others Win US Patents


Roche has been awarded US Patent No. 8,658,109, "Use of a bis-maleic anhydride cross-linking agent for fixation of a cell or tissue sample."

Hans-Peter Josel, Michael Gerg, Rupert Hermann, and Rosa Diaz are named as inventors.

Roche has also been awarded US Patent No. 8,658,366, "Detection of target variants using a fluorescent label and a soluble quencher."

Stephen Will, Amar Gupta, and Laura Geyer are named as inventors.

Becton Dickinson has been awarded US Patent No. 8,658,397, "Assay for detecting closely-related serotypes of human papillomavirus (HPV)."

Chi Chen, Hugh Peck, Michael Porter, Gregory Richart, and Ray McMillian are named as inventors.

Applied Biosystems (Life Technologies) has been awarded US Patent No. 8,658,093, "Devices and methods for the detection of analytes."

Aldrich Lau, Robert Eason, Kristian Scaboo, and Handong Li are named as inventors.

OTC Biotechnologies has been awarded US Patent No. 8,658,613, "Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health."

John Bruno is named as the inventor.

Pacific Biosciences has been awarded US Patent No. 8,658,365, "Nucleic acid synthesis compositions and methods and systems for using same."

Keith Bjornson, Harold Lee, and Jonas Korlach are named as inventors.

Pacific Biosciences has also been awarded US Patent No. 8,658,364, "Isolation of polymerase-nucleic acid complexes."

Thang Pham, Arunashree Bhamidipati, Kevin Travers, Eric Olivares, Tyson Clark, and Jonas Korlach are named as inventors.

Promega has been awarded US Patent No. 8,658,360, "Nucleic acid purification with a binding matrix."

Rex Bitner, Michelle Mandreker, and Paula Brisco are named as inventors.

Samsung has been awarded US Patent No. 8,658,359, "Method and apparatus for disrupting cells and purifying nucleic acid using a single chip."

In-ho Lee, Jun-hong Min, Young-rok Kim, Jae-ho You, Chang-eun Yoo, Jeong-gun Lee, and Ki-woong Han are named as inventors.

Life Technologies has been awarded US Patent No. 8,658,776, "Synthesis of 2',3'-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization."

Zhaochun Ma, Khairuzzaman Mullah, and Robert Eason are named as inventors.

Qiagen has been awarded US Patent No. 8,658,417, "Multiple-input analytical system."

James Godsey, Emmett Brown, Jay Srinivasan, Bandele Jeffrey-Coker, and Jon Willoughby are named as inventors.

Euclid Diagnostics has been awarded US Patent No. 8,658,369, "Methods for evaluating the methylation status of a polynucleotide."

Wadiha Freije and Igor Brikun are named as inventors.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.