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IP Watch: Qiagen, Life Tech, Cepheid, Bio-Rad, Others Win US Patents

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Eppendorf has been awarded US Patent No. 8,728,415, "Microtitration plate."

Martin Seippel is named as the inventor.


Life Technologies (Thermo Fisher Scientific) has been awarded US Patent Nos. 8,728,728 and 8,728,736, both of which are titled "Methods and compositions for multiplex PCR."

John Leamon, Mark Andersen, and Michael Thornton are named as inventors.


Pherecydes Pharma has been awarded US Patent No. 8,728,734, "Method for the random diversification of a genetic sequence while preserving the identity of some inner segments of said genetic sequence."

Francois Iris is named as the inventor.


Canadian Blood Services has been awarded US Patent No. 8,728,735, "Method for the simultaneous determination of blood group and platelet antigen genotypes."

Gregory Denomme is named as the inventor.


Rubicon Genomics has been awarded US Patent No. 8,728,737, "Attaching a stem-loop oligonucleotide to a double-stranded DNA molecule."

Vladimir Makarov, Emmanuel Kamberov, and Brendan Tarrier are named as inventors.


Cepheid has been awarded US Patent No. 8,728,765, "Closed-system multi-stage nucleic acid amplification reactions."

Jesus Ching, Ronald Chang, Douglas Dority, Jian Ping Zhang, James Wang, Wendy Wong, Kendra Paul, and Reuel Van Atta are named as inventors.


Population Genetics has been awarded US Patent No. 8,728,766, "Method of adding a DBR by primer extension."

James Casbon, Sydney Brenner, Robert Osborne, Conrad Lichtenstein, and Andreas Claas are named as inventors.


Bio-Rad has been awarded US Patent No. 8,728,987, "Filtering small nucleic acids using permeabilized cells."

Yanhong Kong, Steven Okino, and Xiangdong Meng are named as inventors.


Qiagen has been awarded US Patent No. 8,729,252, "Method for facilitating an automated isolation of a biopolymer using magnetic particles."

Ralf Himmelreich and Sabine Werner are named as inventors.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.