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IP Watch: Cepheid, Illumina, Sequenom, Bio-Rad, Others Win US Patents

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Cepheid has been awarded US Patent No. 8,709,363, "Cartridge for conducting a chemical reaction."

Kurt Petersen, William McMillan, Farzad Pourahmadi, Ronald Chang, and Douglas Dority are named as inventors.


Illumina has been awarded US Patent No. 8,709,717, "Generation of uniform fragments of nucleic acids using patterned substrates."

Kevin Gunderson, Michal Lebl, and David Heiner are named as inventors.

Illumina was also awarded US Patent No. 8,709,729, "Method of making an array of nucleic acid colonies."

Mostafa Ronaghi and Helmy Eltoukhy are named as inventors.


Riken has been awarded US Patent No. 8,709,721, "Fluorescent molecule and method for detecting target nucleic acid."

Hiroshi Abe, Yoshihiro Ito, Aya Shibata, and Mika Ito are named as inventors.


The President and Fellows of Harvard College have been awarded US Patent No. 8,709,724, "Isothermal amplification of DNA."

Stanley Tabor and Charles Richardson are named as inventors.


Sequenom has been awarded US Patent No. 8,709,726, "Nucleic acid-based tests for prenatal gender determination."

Paul Oeth, Payam Mahboubi, and Min Lee are named as inventors.


Mattias Stromberg, Jenny Goransson, Klas Gunnarsson, Mats Nilsson, Peter Svedlindh, and Maria Stromme have been awarded US Patent No. 8,709,727, "Magnetic detection of small entities."

Several of the inventors are affiliated with Uppsala University.


Bio-Rad has been awarded US Patent No. 8,709,762, "System for hot-start amplification via a multiple emulsion."

Benjamin Hindson is named as the inventor.


BioMérieux has been awarded US Patent No. 8,709,779, "Newly identified human rhinovirus of HRV-C and methods and kits for detecting HRV-Cs."

Richard Gonzalez, Jianwei Wang, Zichun Xiang, and Kunling Shen are named as inventors.


Handylab has been awarded US Patent No. 8,709,787, "Microfluidic cartridge and method of using same."

Kalyan Handique is named as the inventor.


Gen-Probe (Hologic) has been awarded US Patent No. 8,709,814, "Method for incubating the contents of a receptacle."

Kelly Ammann, Robert Schneider, and Robert Smith are named as inventors.


Applied Biosystems (Thermo Fisher Scientific) has been awarded US Patent No. 8,710,208, "Method to quantify siRNAs, miRNAs and polymorphic miRNAs."

Ruoying Tan, Caifu Chen, and Karl Guegler are named as inventors.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.