Skip to main content
Premium Trial:

Request an Annual Quote

DiaCarta, Arrow Diagnostics Ink Italian Distribution Deal for CRC Test

NEW YORK (GenomeWeb) – DiaCarta said today it has signed an agreement making Arrow Diagnostics the sole distributor for the firm's ColoScape colorectal cancer test in Italy, San Marino, and Vatican City.

ColoScape is a CE-marked qPCR-based kit that uses DiaCarta's proprietary QClamp method — a technique that uses xenonucleic acid to "clamp," or silence, amplification of non-mutant DNA in heterogeneous samples — to detect 20 mutation markers from four oncogenes. The test requires as little as 20 ng of DNA from formalin-fixed, paraffin embedded tumor tissue, stool, or plasma samples. It runs on standard real-time PCR platforms and takes two-and-a-half hours.

"The partnership with DiaCarta will generate significant value for our customers," Arrow CEO Gianluigi Mascarino said in a statement. He noted that Arrow was "impressed" with DiaCarta's QClamp xenonucleic clamping technology as well as the company's "commitment to innovation," and believes the ColoScape test "will make a significant impact on colorectal cancer."

DiaCarta presented data last year supporting the use of the test as a liquid biopsy, and earlier this year the firm completed a Series B funding round, raising a total of $45 million.

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.