NEW YORK – Like performing one giant pooling test, assessing sewage for SARS-CoV-2 has the potential to localize hotspots of COVID-19 infection. Municipalities around the world are now beginning to scale up nascent wastewater-based epidemiology programs using standard commercially available extraction and PCR kits, as well as new products designed for SARS-CoV-2 detection from wastewater, and start-ups have begun offering testing and epidemiology consulting services.