Combined NGS, ddPCR Method Reveals Integer Copy Numbers for Multiallelic CNVs

Jan 29, 2015

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NEW YORK(GenomeWeb) – Copy numbers of certain elements in the human genome vary over wide ranges and exist in more states than can be accounted for with two-allele models. These multi-allelic copy number variation loci, or mCNVs, have proven challenging to study, and past work has yielded non-integer estimates of population-wide distributions of copy numbers.

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