Catalyst-Based Thermodynamics Method Could Enable Improvements in DNA Oligo Design

Jan 26, 2016

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NEW YORK (GenomeWeb) – Researchers at Rice University have developed a catalyst-based method for determining melting properties of oligonucleotides.

The method, published last week in Nature Communications, can be used to more accurately determine DNA hybridization thermodynamics, and may enable improvements to oligonucleotide construction for applications such as making PCR primers.

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