Researchers uncovered rare, damaging mutations in genes involved in early brain development among 22 percent of 381 sporadic congenital hydrocephalus cases.
The randomized, Phase II trial will test ctDNA-guided second-line adjuvant therapy for stage II and III hormone receptor-positive, HER-2 negative breast cancer.
In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.
Researchers profiled T cells in the cerebrospinal fluid of healthy individuals and multiple sclerosis patients using single-cell RNA-seq and T cell receptor sequencing.
In Genome Biology this week: improved reference genome for the Asian tiger mosquito Aedes albopictus, links between Ebola variants and outcomes, and more.
In Genome Biology this week: analysis of tuberculosis samples from the 1600s, tool to detect variants affecting RNA-binding protein activity, and more.
A saliva-based test for COVID-19 that got help from the National Basketball Association has received Emergency Use Authorization, according to the Wall Street Journal.
The test could be used in most high-complexity labs because it has been authorized for use with different combinations of frequently used reagents and instruments.
A new UK government says socioeconomic factors, not genetics, account for disparities in deaths due to COVID-19 between ethnic groups, the Financial Times reports.
