Whitehead Institute Lung Cancer Metastasis Study Relies on CRISPR-Based Method to Track Single-Cell Lineages Researchers traced the development of thousands of engineered human lung cancer cells within a mouse model of disease to examine metastasis. DNA Methylation Editing Rescues Neurons in Fragile X Syndrome Whitehead Institute researchers were able to restore nearly full FMR1 expression in a fragile X syndrome iPSC cell line. Broad-Led Study Finds Three New HIV Host Factors, Possible Drug Targets A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5. CRISPR Screen Reveals Genes Essential to Toxoplasmosis, Malaria Parasites A Whitehead Institute-led study has revealed genes essential to one-celled parasites causing human diseases, which have resisted gene-editing techniques. CRISPR Use in Cancer Research, Searching for Druggable Targets Discussed at AACR At one panel of the AACR conference in New Orleans this week, researchers discussed their labs' efforts to develop screens using CRISPR. Oct 16, 2015 Broad, Whitehead Team Uses Dual-Technology Screen to Identify Essential Genes in Human Genome Sep 29, 2015 Court Rules Against University of Utah in RNAi IP Inventor Dispute Jan 29, 2015 AstraZeneca Launches Four New Collaborations to Feature CRISPR in R&D Apr 23, 2014 Studies Describe Mammalian Y Chromosome Evolution, Recent Stability Mar 26, 2014 Biogen Idec Provides $5.3M for Collaboration with Whitehead Scientists Jul 22, 2013 Refined X Chromosome Assembly Hints at Possible Role in Sperm Production Feb 5, 2013 Study Uncovers Coordinated Transcription for Protein-Coding and RNAs Jan 17, 2013 Research Exposes Vulnerabilities in Security of Public Genomic Databases Jul 19, 2012 UMass Aims to Stay Tuschl IP Dispute as University of Utah Argues to Keep It Moving Premium Jun 28, 2012 UMass Files Appeal over Rejection of Its RNAi IP Litigation Dismissal Request Premium May 17, 2012 University of Utah Aims to Keep RNAi IP Suit Against UMass Officials on Track Premium Feb 22, 2012 Men Still Manly: Y Chromosome Not Going Away Nov 3, 2011 UMass, Other Defendants Seek Dismissal of University of Utah Tuschl-II IP Lawsuit Premium Jul 21, 2011 Q&A: Whitehead's Richard Possemato on RNAi Screening in Breast Cancer Premium Jul 14, 2011 In Amended Suit over Tuschl-II IP Inventorship, University of Utah Restates Role of Researcher Premium Apr 12, 2011 Rare Disease Gene Detected Using Exome Sequencing, Disease Network Approach Mar 17, 2011 Alnylam, Max Planck Settle Suit Over Tuschl IP Premium Mar 4, 2010 MIT Seeks Dismissal from Tuschl IP Litigation Premium Jan 28, 2010 In Court Filing, Alnylam, Max Planck Question UMass Ownership of Tuschl-I IP Premium Jan 28, 2010 Timeline of Events Leading to Tuschl IP Litigation Premium Load More Breaking News Sequencing Study Uncovers MERS-Related Coronavirus in Swiss Bats Angstrom Bio Raises $3M in Private Financing Eagle Biosciences, Genetic Analysis Ink Distribution Agreement for Gut Microbiota Test Centogene Q1 Revenues Grow More Than Fivefold Driven by COVID-19 Testing Epizyme Partnering With Quest Diagnostics for Lymphoma Mutation Testing Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel The Scan CDC Calls Delta "Variant of Concern" CNN reports the US Centers for Disease Control and Prevention now considers the Delta variant of SARS-CoV-2 to be a "variant of concern." From FDA to Venture Capital Former FDA Commissioner Stephen Hahn is taking a position at a venture capital firm, leading some ethicists to raise eyebrows, according to the Washington Post. Consent Questions Nature News writes that there are questions whether informed consent was obtained for some submissions to a database of Y-chromosome profiles. Cell Studies on Multimodal Single-Cell Analysis, Coronaviruses in Bats, Urban Microbiomes In Cell this week: approach to analyze multimodal single-cell genomic data, analysis of bat coronaviruses, and more.