Whitehead Institute

This Week in PNAS

In PNAS this week: genetic hints of adaptive evolution in Atlantic herring, ancestry of ancient individuals from the Pacific Northwest, and more.

A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.

Susan Lindquist Dies

Protein researcher and former Whitehead Institute director Susan Lindquist has died.

A Whitehead Institute-led study has revealed genes essential to one-celled parasites causing human diseases, which have resisted gene-editing techniques.

At one panel of the AACR conference in New Orleans this week, researchers discussed their labs' efforts to develop screens using CRISPR.

The researchers also identified genes involved in cancer cell proliferation and survival that could potentially be used as new drug targets.

The court found that the university had failed to demonstrate that one of its researchers had collaborated with the IP's inventors and therefore is not entitled to co-inventorship.

The partners are the Wellcome Trust Sanger Institute, The Innovative Genomics Initiative, Thermo Fisher Scientific, and the Broad and Whitehead Institutes.

NEW YORK (GenomeWeb) – A pair of studies appearing online today in Nature are uncovering evolutionary patterns for the mammalian Y chromosome and revealing conserved Y chromosome sequences stemming from ancestral, dosage-sensitive genes that have acquired functions outside of the male re

NEW YORK (GenomeWeb News) – Scientists at the Whitehead Institute will use $5.3 million over the next three years from Biogen Idec to pursue research projects involving genomics, genetics, immunology, neurology, developmental biology, and other approaches.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.