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Whitehead Institute

Researchers traced the development of thousands of engineered human lung cancer cells within a mouse model of disease to examine metastasis.

In Genome Research this week: Y chromosome gene expression analysis, de novo mutations rise with paternal age in rhesus macaques, and more.

In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.

In PNAS this week: early-onset preeclampsia model, lateral gene transfer events in grasses, and more.

Whitehead Institute researchers were able to restore nearly full FMR1 expression in a fragile X syndrome iPSC cell line.

In PNAS this week: genetic hints of adaptive evolution in Atlantic herring, ancestry of ancient individuals from the Pacific Northwest, and more.

A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.

Susan Lindquist Dies

Protein researcher and former Whitehead Institute director Susan Lindquist has died.

A Whitehead Institute-led study has revealed genes essential to one-celled parasites causing human diseases, which have resisted gene-editing techniques.

At one panel of the AACR conference in New Orleans this week, researchers discussed their labs' efforts to develop screens using CRISPR.

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A survey by Nature finds that most researchers want scientific meetings to continue virtually or with a virtual component, even after the pandemic ends.

Bloomberg reports that the B.1.351 SARS-CoV-2 viral variant could prompt the formulation of better vaccines.

Certain blood proteins may be able to distinguish COVID-19 patients who will become critically ill from those who will not, the Atlanta Journal-Constitution reports.

In Genome Biology this week: algorithm to assess regulatory features, approach to integrate multiple single-cell RNA-seq datasets, and more.