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Whitehead Institute

In Genome Research this week: Y chromosome gene expression analysis, de novo mutations rise with paternal age in rhesus macaques, and more.

In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.

In PNAS this week: early-onset preeclampsia model, lateral gene transfer events in grasses, and more.

Whitehead Institute researchers were able to restore nearly full FMR1 expression in a fragile X syndrome iPSC cell line.

In PNAS this week: genetic hints of adaptive evolution in Atlantic herring, ancestry of ancient individuals from the Pacific Northwest, and more.

A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.

Susan Lindquist Dies

Protein researcher and former Whitehead Institute director Susan Lindquist has died.

A Whitehead Institute-led study has revealed genes essential to one-celled parasites causing human diseases, which have resisted gene-editing techniques.

At one panel of the AACR conference in New Orleans this week, researchers discussed their labs' efforts to develop screens using CRISPR.

The researchers also identified genes involved in cancer cell proliferation and survival that could potentially be used as new drug targets.

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The World Health Organization will be providing low-cost COVID-19 tests to low- and middle-income nations, according to Reuters.

Nature News examines how the confirmation of Amy Coney Barrett to the US Supreme Court could affect scientific agencies.

Nobel Prize-winner Arthur Ashkin, who developed optical tweezers, has died at 98, the Washington Post reports.

In PNAS this week: altered gene expression in brain samples from Alzheimer's disease patients, effects of gene mutations found in bladder cancer, and more.