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Wellcome Trust

Areas of concern are the recruitment of talented scientists, as well as retaining access to EU funding, European research collaborations, and clinical trials.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.

Scientists from The Wellcome Trust Sanger Institute, Public Health England, and elsewhere sequenced the genomes of 209 MRSA isolates collected in Europe from 1960 to 1989.

The institute will house the Centre for Genomic Pathogen Surveillance to monitor antibiotic-resistant bacteria worldwide.

Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.

Researchers led by the Wellcome Trust Sanger Institute also reported that combined chromothripsis and amplification might be a driving mechanism of osteosarcoma.

Wellcome Trust's Jeremy Farrar discusses the effect of Brexit on science in the UK in The Times.

Isolated Variants

By studying isolated villagers, researchers have uncovered a variant that appears to protect against cardiovascular disease.

The researchers used SC3 to uncover subclones within samples from patients with pre-malignant tumors.

Researchers found mutations thought to be associated with embryo development and used them to recreate early cellular life in the human body.

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A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.