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The researchers created a resource of cancer dependencies and developed a framework to prioritize existing cancer drug targets and suggest new ones.
The researchers studied edits generated by more than 40,000 gRNAs and gathered data for more than 109 mutational outcomes to create the software.
Deciphering Developmental Disorders study researchers estimated the portion of recessive coding diagnoses among patients of European and Pakistani ancestry.
Researchers identified gene family expansions and other parasitic adaptations using genome sequences for 81 roundworms or flatworms.
The Wellcome Trust and the Bill & Melinda Gates Foundation have joined the open-access initiative Plan S, according to ScienceInsider.
The Darwin Tree of Life Project aims to sequence the genetic codes of 66,000 different species in the UK as part of the Earth BioGenome Project.
The Guardian reports that senior management at the Wellcome Sanger Institute is under investigation after allegations of bullying and discrimination.
Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.
Wellcome Sanger Institute researchers showed that Cas9-induced DNA breaks frequently resolved into deletions extending over many kilobases in the genome.
The Wellcome Trust has announced that it is starting a new program to fund risky research ideas, Science reports.
A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.
Nature News writes that viral genomic surveillance in the US faces systemic issues.
President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.
In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.