Wellcome Trust

All Together

Jeremy Farrar, the director of the Wellcome Trust, writes at the Guardian that science is a team endeavor.

Researchers saw mismatch repair-related mutations in a significant subset of breast cancers, hinting at potential response to checkpoint blockade immunotherapy.

Areas of concern are the recruitment of talented scientists, as well as retaining access to EU funding, European research collaborations, and clinical trials.

This Week in Cell

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.

Scientists from The Wellcome Trust Sanger Institute, Public Health England, and elsewhere sequenced the genomes of 209 MRSA isolates collected in Europe from 1960 to 1989.

The institute will house the Centre for Genomic Pathogen Surveillance to monitor antibiotic-resistant bacteria worldwide.

Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.

Researchers led by the Wellcome Trust Sanger Institute also reported that combined chromothripsis and amplification might be a driving mechanism of osteosarcoma.

Wellcome Trust's Jeremy Farrar discusses the effect of Brexit on science in the UK in The Times.

Isolated Variants

By studying isolated villagers, researchers have uncovered a variant that appears to protect against cardiovascular disease.

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New Mexico is re-doing its proposed science education standards after criticism, the Associated Press reports.

Agbio executives say gene editing will speed up breeding efforts, according to the Wall Street Journal.

La Trobe University's Jenny Graves has won the $250,000 Prime Minister's Prize for Science, the Guardian reports.

In Cell this week: post-treatment changes to melanoma genome, multi-omics analysis of muscle-invasive bladder cancer, and more.