Based on genetic patterns in thousands of individuals with primary sclerosing cholangitis, researchers identified four new risk loci and explored ties to IBD.
The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.
Illumina and the H3Africa Consortium hope the array will allow future GWAS to address African genomic diversity in a way that previous chips have not.
The partners will exchange all information they have on genetic mutations leading to cancer with an eye toward accelerating research and drug discovery efforts.
Researchers found distinct genetic differences in the two forms of CHD and discovered three new rare CHD disorders in children.
The updated repository includes 265 drugs, 1,074 cell lines, as well as associated whole-exome sequencing and gene expression data among other datasets.
The Human Cancer Models Initiative aims to create about 1,000 cancer cell lines that scientists can use to study tumor progression, drug resistance, and more.
A UK research team performed single-cell RNA sequencing on epiblast cells to learn more about how gene expression directs organ formation.
The Wellcome Trust, the Max Planck Society, and the Howard Hughes Medical Institute will continue to support the open-access journal eLife, according to Nature News.
Stat News profiles the Wellcome Trust's Jeremy Farrar.
In Science this week: metagenomic-based technique for determining protein structure, and more.
An academic laments the rise of narcissism in the sciences, the Guardian reports.
Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.
The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.