The researchers studied edits generated by more than 40,000 gRNAs and gathered data for more than 109 mutational outcomes to create the software.
Deciphering Developmental Disorders study researchers estimated the portion of recessive coding diagnoses among patients of European and Pakistani ancestry.
Researchers identified gene family expansions and other parasitic adaptations using genome sequences for 81 roundworms or flatworms.
The Wellcome Trust and the Bill & Melinda Gates Foundation have joined the open-access initiative Plan S, according to ScienceInsider.
The Darwin Tree of Life Project aims to sequence the genetic codes of 66,000 different species in the UK as part of the Earth BioGenome Project.
The Guardian reports that senior management at the Wellcome Sanger Institute is under investigation after allegations of bullying and discrimination.
Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.
Wellcome Sanger Institute researchers showed that Cas9-induced DNA breaks frequently resolved into deletions extending over many kilobases in the genome.
The Wellcome Trust has announced that it is starting a new program to fund risky research ideas, Science reports.
Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.
Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.
The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.
ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.
In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.