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Wellcome Sanger Institute

Several studies describe a new Neanderthal genome, Neanderthal sequence effects on human traits, and ancient hunter-gatherer population social structure clues.

Data from hundreds of individuals suggest that the country's populations are genetically diverse, with a long history of genetic isolation and differentiation.

With sequence data for hundreds of advanced breast cancer samples, investigators identified genetic alterations shared with — and distinct from — those in primary tumors.

Investigators sequenced 3,700-year-old Canaanite genomes and compared them to present-day populations to explore the historical people's origin and fate.

Scientists from The Wellcome Trust Sanger Institute, Public Health England, and elsewhere sequenced the genomes of 209 MRSA isolates collected in Europe from 1960 to 1989.

The institute will house the Centre for Genomic Pathogen Surveillance to monitor antibiotic-resistant bacteria worldwide.

Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.

Effect of Sex

Researchers find a number of traits differ by sex and could affect mouse model studies, according to Reuters.

Even in schizophrenia cases lacking intellectual disability, investigators found that rare mutations in genes normally resistant to loss-of-function changes were enriched.

Researchers saw an over-representation of rarer variants in isolated groups when they sequenced thousands of individuals from 10 European populations.

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Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.

Noel Rose, the "father of autoimmunity," has died at 92, the Washington Post reports.

According to CNN, Legionella was discovered in buildings leased by the Centers for Disease Control and Prevention as they reopened following coronavirus pandemic-related closures.

In PLOS this week: genetic analysis of malaria parasite populations in Southeast Asia, genomic surveillance of yellow fever virus in São Paulo, and more.