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Wellcome Sanger Institute

Using a new mathematical model, researchers uncovered mutational signatures related to homologous recombination deficiency in up to one-fifth of breast cancers.

A retrospective analysis of Enterococcus faecium isolates from a UK hospital provided clues to infection sources and antibiotic resistance patterns.

The new sequences also uncovered two new gene families likely involved in Plasmodium malariae's ability to invade host cells.

Investigators uncovered 33 hotspots of large tandem duplications among breast cancer cases that affected cancer susceptibility genes and super-enhancers.

The researchers said their one-step, inducible, multiplex gene knockdown and gene knockout platforms can be used in many differentiated cell types.

The Bridget Ogilvie Building will house sequencing facilities, and the Biodata Innovation Centre will host genomic startups.

Two new studies are exploring genomic features and population variation in the river blindness-causing parasite Onchocerca volvulus.

A sequencing study suggests multidrug-resistant Mycobacterium abscessus bacteria are often passed between people, not acquired from the environment.

Two independent research teams linked plasmepsin 2 and plasmepsin 3 gene amplifications to piperaquine resistance.

By analyzing mutations in tumors from a broad swath of tobacco smoke-related cancer types, investigators identified more than two-dozen mutational signatures.

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Bloomberg Law writes that the Genetic Information Nondiscrimination Act may work better as a privacy, rather than anti-discrimination, law.

TechCrunch reports that Linda Avey has a new personal genomics startup that's focusing on India.

A new report finds that though the US has increased its activity in science and engineering, its global share of that activity has fallen in some areas, according to Inside Higher Ed.

In Nature this week: genomic analysis of rapeseed, universal target enrichment method for metagenomic sequencing, and more.