Two independent research teams linked plasmepsin 2 and plasmepsin 3 gene amplifications to piperaquine resistance.
By analyzing mutations in tumors from a broad swath of tobacco smoke-related cancer types, investigators identified more than two-dozen mutational signatures.
The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.
An international team analyzed the genomes of 65 wild-born chimpanzees and 10 bonobos to uncover evidence of gene flow.
Using sequence data for more than 1,800 Salmonella enterica serovar Typhi isolates, researchers identified 68 SNPs to trace the bug to its geographical source.
Genome sequencing suggests secondary tumors present after ionizing radiation treatment tend to contain numerous deletions and balancing inversions.
Different clades of Salmonella enterica serovar Enteritidis are behind the self-limiting and invasive diseases the bacterium causes in different parts of the world.
Using genome sequence data from almost 65,000 individuals, researchers identified 39.2 million SNPs that can be applied to improved genotyping imputation.
The project has recruited nearly half of the 1,000 families it plans to analyze and has completed the exome analysis for about 160.
Researchers found distinct genetic differences in the two forms of CHD and discovered three new rare CHD disorders in children.
At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.
The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.
Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.
In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.